Membrane-spanning 4-domains subfamily A member 3 is a protein that in humans is encoded by the MS4A3 gene.

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.

Interactions

MS4A3 has been shown to interact with CDKN3.

References

Further reading




Frontiers Role of the membranespanning 4A gene family in lung

MS4A13 Gene GeneCards M4A13 Protein M4A13 Antibody

Myogenic Differentiation and Immunomodulatory Properties of Rat Adipose

MS4A3 Gene GeneCards MS4A3 Protein MS4A3 Antibody

Incidence and classification of MS4A gene mutations in lung